|
KMID : 0356919930260030499
|
|
Korean Journal of Anesthesiology
1993 Volume.26 No. 3 p.499 ~ p.505
|
|
|
The Change of Plasma Concentrations of Fibrinogen Degradation Proudcts and Fibrin Degradation Products During the Open Heart Surgery
|
|
류승철
우성/조강회/구영권/박성섭
|
|
|
Abstract
|
|
|
There were many researches, which qualitative or quantitative assays were performed about fibrinolysis and the degree of activation of coagulation system. Authors measured fibrinogen degradation products(FgDP) and fibrin degradation
products(FbDP)
by
monoclonal enzymeimmunoassay, instead of polyclonal method in 12 cases of cardiopulmonary bypass(CPB).
1) The increase of FgDP after sternotomy is verifying the significant fibrino(geno) lysis occured by stimulation of sternotomy.
2) By the result that FgDP was significantly increased compared with FbDP, primary fibrinogenolysis is more important phenomenon than secondary fibrinolysis during CPB.
3) FbDP and FgDP were most signficantly increased immediately before the end of CPB and after CPB.
4) increased FgDP was decreased after CPB but FbDP was still elevated 5 hours after CPB.
According to the above results, CPB induced primary fibrinogenolysis and secondary fibrinolysis in open heart surgery.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|